Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma

Molecular Mechanisms: Connections between Nonalcoholic Fatty Liver Disease, Steatohepatitis and Hepatocellular Carcinoma

Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH), causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The patatin-like phospholipase-3 (PNPLA3) I148M sequence variant is one of the strongest genetic determinants of NAFLD/NASH. PNPLA3 is an in...

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Bibliographic Details
Main Authors: Tatsuo Kanda, Taichiro Goto, Yosuke Hirotsu, Ryota Masuzaki, Mitsuhiko Moriyama, Masao Omata
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
dysbiosis
hcc
hsd17b13
nafld
nash
metabolic syndrome
microbiota
obesity
pnpla3
Online Access:https://www.mdpi.com/1422-0067/21/4/1525

Internet

https://www.mdpi.com/1422-0067/21/4/1525

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