Bleomycin Aggravates Atopic Dermatitis via Lung Inflammation in 2,4-Dinitrochlorobenzene-Induced NC/Nga Mice

Bleomycin Aggravates Atopic Dermatitis via Lung Inflammation in 2,4-Dinitrochlorobenzene-Induced NC/Nga Mice

Atopic dermatitis (AD) is a chronic inflammatory skin disease. Bleomycin (BLM) contributes to the induction of pulmonary inflammation and fibrosis in animals. Although skin and lung tissue inflammation is closely related in the pathogenesis of allergic diseases, a proper animal model for investigati...

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Bibliographic Details
Main Authors: Yoon-Young Sung, Seung-Hyung Kim, Won-Kyung Yang, Yang-Chun Park, Ho Kyoung Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
bleomycin
CD4+ cells
dinitrochlorobenzene
hyperresponsiveness
lung
pulmonary fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00578/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00578/full

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