Membrane dynamics shape TCR-generated signaling

Despite intensive investigation, the mechanisms of TCR-mediated signal generation remain poorly understood. Here we review various dynamic processes at the cell membrane that might critically control this signaling. Firstly, we summarize recent reports providing new information on the sensitivity o...

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Bibliographic Details
Main Authors: Hai-Tao eHe, Pierre eBongrand
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00090/full