Multiparametric characterization of white matter alterations in early stage Huntington disease

Multiparametric characterization of white matter alterations in early stage Huntington disease

Abstract Huntington’s disease (HD) is a monogenic, fully penetrant neurodegenerative disorder. Widespread white matter damage affects the brain of patients with HD at very early stages of the disease. Fixel-based analysis (FBA) is a novel method to investigate the contribution of individual crossing...

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Bibliographic Details
Main Authors: Isaac M. Adanyeguh, Francesca Branzoli, Cécile Delorme, Aurélie Méneret, Marie-Lorraine Monin, Marie-Pierre Luton, Alexandra Durr, Emanoel Sabidussi, Fanny Mochel
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92532-1

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https://doi.org/10.1038/s41598-021-92532-1

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