Phloroglucinol attenuates motor functional deficits in an animal model of Parkinson's disease by enhancing Nrf2 activity.

In this study, we investigated whether phloroglucinol (1,3,5-trihydroxybenzene) has therapeutic effects in cellular and animal model of Parkinson's disease (PD). PD is the second most common, chronic and progressive neurodegenerative disease, and is clinically characterized with motor dysfuncti...

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Main Authors: Junghwa Ryu, Rui Zhang, Bo-Hyun Hong, Eun-Jung Yang, Kyoung Ah Kang, Moonseok Choi, Ki Cheon Kim, Su-Jin Noh, Hee Soo Kim, Nam-Ho Lee, Jin Won Hyun, Hye-Sun Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3748069?pdf=render