Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants

Alzheimer's disease is widely held to be associated with oxidative stress due, in part, to the membrane action of amyloid β-peptide (Aβ) aggregates. In this study, the involvement of oxidative stress on Aβ-induced energy metabolism dysfunction was evaluated on PC12 cells. It was shown that Aβ p...

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Bibliographic Details
Main Authors: Cláudia Pereira, Maria Sancha Santos, Catarina Oliveira
Format: Article
Language:English
Published: Elsevier 1999-06-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996199902413