Mithramycin delivery systems to develop effective therapies in sarcomas

Mithramycin delivery systems to develop effective therapies in sarcomas

Abstract Background Sarcomas comprise a group of aggressive malignancies with very little treatment options beyond standard chemotherapy. Reposition of approved drugs represents an attractive approach to identify effective therapeutic compounds. One example is mithramycin (MTM), a natural antibiotic...

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Bibliographic Details
Main Authors: Óscar Estupiñán, Enrique Niza, Iván Bravo, Verónica Rey, Juan Tornín, Borja Gallego, Pilar Clemente-Casares, Francisco Moris, Alberto Ocaña, Verónica Blanco-Lorenzo, Mar Rodríguez-Santamaría, Aitana Vallina-Álvarez, M. Victoria González, Aida Rodríguez, Daniel Hermida-Merino, Carlos Alonso-Moreno, René Rodríguez
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Nanobiotechnology
Subjects:
Mithramycin
Sarcoma
Soft tissue sarcoma
Chondrosarcoma
Polymeric nanoparticles
Polylactide
Online Access:https://doi.org/10.1186/s12951-021-01008-x

Internet

https://doi.org/10.1186/s12951-021-01008-x

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