Dopaminergic dysregulation in prefrontal cortex of rhesus monkeys following cocaine self-administration

Chronic cocaine administration regulates the expression of several proteins related to dopaminergic signaling and synaptic function in the mesocorticolimbic pathway, including the prefrontal cortex. Functional abnormalities in the prefrontal cortex are hypothesized to be due in part to the expressio...

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Bibliographic Details
Main Authors: Scot eMcIntosh, Leonard H Howell, Scott E Hemby
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00088/full