Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence

Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence

Aspergillus fumigatus is a saprophytic mold that can cause life-threatening infections in immunocompromised patients. In the lung, inhaled conidia are confronted with immune effector cells that attack the fungus by various mechanisms such as phagocytosis, production of antimicrobial proteins or gene...

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Bibliographic Details
Main Authors: Katrin eLapp, Martin eVödisch, Kristin eKroll, Maria eStrassburger, Olaf eKniemeyer, Thorsten eHeinekamp, Axel A Brakhage
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Microbiology
Subjects:
Aspergillosis
Aspergillus fumigatus
Nitric Oxide
Virulence
reactive nitrogen intermediates
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00469/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00469/full

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