Accumulation of Tc-99m HL91 in Tumor Hypoxia: In Vitro Cell Culture and In Vivo Tumor Model

Hypoxic cells within a tumor can account, in part, for resistance to radiotherapy and chemotherapy. Indeed, the oxygenation status has been shown to be a prognostic marker for the outcome of therapy. The purpose of this study was to determine whether Tc-99m HL91 (HL91), a noninvasive imaging tracer,...

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Bibliographic Details
Main Authors: Bi-Fang Lee, Nan-Tsing Chiu, Chien-Chung Hsia, Lie-Hang Shen
Format: Article
Language:English
Published: Wiley 2008-09-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X09700038