The association of CYP2D6 gene polymorphisms in the full-length coding region with higher recurrence rate of vivax malaria in Yunnan Province, China

The association of CYP2D6 gene polymorphisms in the full-length coding region with higher recurrence rate of vivax malaria in Yunnan Province, China

Abstract Background Accumulating evidence suggest that compromised CYP2D6 enzyme activity caused by gene mutation could contribute to primaquine failure for the radical cure of vivax malaria. The current study aims to preliminarily reveal the association between the recurrence of vivax malaria in Yu...

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Bibliographic Details
Main Authors: Herong Huang, Ying Dong, Yanchun Xu, Yan Deng, Canglin Zhang, Shuping Liu, Mengni Chen, Yan Liu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Malaria Journal
Subjects:
Plasmodium vivax
Relapse
CYP2D6 gene
Coding region
Primaquine
Allele
Online Access:https://doi.org/10.1186/s12936-021-03685-3

Internet

https://doi.org/10.1186/s12936-021-03685-3

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