Comparison of Mutation Profiles in the Duchenne Muscular Dystrophy Gene among Populations: Implications for Potential Molecular Therapies

Comparison of Mutation Profiles in the Duchenne Muscular Dystrophy Gene among Populations: Implications for Potential Molecular Therapies

Novel therapeutic approaches are emerging to restore dystrophin function in Duchenne Muscular Dystrophy (DMD), a severe neuromuscular disease characterized by progressive muscle wasting and weakness. Some of the molecular therapies, such as exon skipping, stop codon read-through and internal ribosom...

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Bibliographic Details
Main Authors: Luz Berenice López-Hernández, Benjamín Gómez-Díaz, Alexandra Berenice Luna-Angulo, Mónica Anaya-Segura, David John Bunyan, Carolina Zúñiga-Guzman, Rosa Elena Escobar-Cedillo, Bladimir Roque-Ramírez, Luis Angel Ruano-Calderón, Héctor Rangel-Villalobos, Julia Angélica López-Hernández, Francisco Javier Estrada-Mena, Silvia García, Ramón Mauricio Coral-Vázquez
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:International Journal of Molecular Sciences
Subjects:
Ataluren
DMD gene
MLPA
exon skipping
Duchenne
therapies
Online Access:http://www.mdpi.com/1422-0067/16/3/5334

Internet

http://www.mdpi.com/1422-0067/16/3/5334

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