Modulation of the inhibitory receptor leukocyte Ig-like receptor 1 on human natural killer cells

Leukocyte Ig-like receptor 1 (LIR-1) is an inhibitory Ig superfamily receptor with broad specificity for MHC-I expressed on leukocytes including natural killer (NK) and T cells. The extent of LIR-1 expression on NK cells is quite disparate between donors but the regulation of LIR-1 in NK cells is po...

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Bibliographic Details
Main Authors: Nicholas L. Li, Chelsea L. Davidson, Atul eHumar, Deborah N. Burshtyn
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00046/full