Hepatocyte expression of the senescence marker p21 is linked to fibrosis and an adverse liver-related outcome in alcohol-related liver disease.

Hepatocyte expression of the senescence marker p21 is linked to fibrosis and an adverse liver-related outcome in alcohol-related liver disease.

<h4>Background and aim</h4>Alcohol-related liver disease (ALD) remains a leading cause of liver-related morbidity and mortality. Age, fibrosis stage, MELD score and continued alcohol consumption predict outcome in everyday clinical practice. In previous studies increased hepatocyte nucle...

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Bibliographic Details
Main Authors: Aloysious Aravinthan, Giada Pietrosi, Matthew Hoare, James Jupp, Aileen Marshall, Clare Verrill, Susan Davies, Adrian Bateman, Nick Sheron, Michael Allison, Graeme J M Alexander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086266/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086266/?tool=EBI

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