Complete suppression of the gut microbiome prevents acute graft-versus-host disease following allogeneic bone marrow transplantation.

The hypothesis that elimination of facultative and strict anaerobic microorganisms from the gastro-intestinal tract by antimicrobial drugs in the period of time around allogeneic bone marrow transplantation (BMT) prevents acute graft-versus-host disease (GVHD), was examined in a cohort of 112 childr...

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Bibliographic Details
Main Authors: Jaak M Vossen, Harry F L Guiot, Arjan C Lankester, Ann C T M Vossen, Robbert G M Bredius, Ron Wolterbeek, Hanny D J Bakker, Peter J Heidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4152127?pdf=render