Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss

Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss

Abstract Regulators of G protein signaling (RGS) accelerate the GTPase activity of G proteins to enable rapid termination of the signals triggered by G protein-coupled receptors (GPCRs). Activation of several GPCRs, including cannabinoid receptor 2 (CB2R) and adenosine A1 receptor (A1AR), protects a...

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Bibliographic Details
Main Authors: Asmita Dhukhwa, Raheem F. H. Al Aameri, Sandeep Sheth, Debashree Mukherjea, Leonard Rybak, Vickram Ramkumar
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87387-5

Internet

https://doi.org/10.1038/s41598-021-87387-5

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