Ectonucleotidases in Acute and Chronic Inflammation

Ectonucleotidases in Acute and Chronic Inflammation

Ectonucleotidases are extracellular enzymes with a pivotal role in inflammation that hydrolyse extracellular purine and pyrimidine nucleotides, e.g., ATP, UTP, ADP, UDP, AMP and NAD+. Ectonucleotidases, expressed by virtually all cell types, immune cells included, either as plasma membrane-associate...

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Bibliographic Details
Main Authors: Anna Lisa Giuliani, Alba Clara Sarti, Francesco Di Virgilio
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pharmacology
Subjects:
ecto-nucleotidases
ATP
purinergic receptors
immune cells
acute inflammation
chronic inflammatory diseases
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.619458/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.619458/full

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