Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia: implication for malaria diagnosis

Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia: implication for malaria diagnosis

Abstract Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2(HRP2) are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the PfHRP3 antigen contributes to the detection of P. falciparum infections in PfHRP2 RDTs. However, the performance HRP2-base...

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Bibliographic Details
Main Authors: Gezahegn Solomon Alemayehu, Kayla Blackburn, Karen Lopez, Cheikh Cambel Dieng, Eugenia Lo, Daniel Janies, Lemu Golassa
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Pfhrp2/3 gene deletion
PfHRP2 RDT
Microscopy
PCR
Assosa
Online Access:https://doi.org/10.1186/s12936-021-03629-x

Internet

https://doi.org/10.1186/s12936-021-03629-x

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