Integrative bioinformatics identifies postnatal lead (Pb) exposure disrupts developmental cortical plasticity

Integrative bioinformatics identifies postnatal lead (Pb) exposure disrupts developmental cortical plasticity

Abstract Given that thousands of chemicals released into the environment have the potential capacity to harm neurodevelopment, there is an urgent need to systematically evaluate their toxicity. Neurodevelopment is marked by critical periods of plasticity wherein neural circuits are refined by the en...

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Bibliographic Details
Main Authors: Milo R. Smith, Priscilla Yevoo, Masato Sadahiro, Christine Austin, Chitra Amarasiriwardena, Mahmoud Awawda, Manish Arora, Joel T. Dudley, Hirofumi Morishita
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Scientific Reports
Subjects:
Critical Period
Integrated Bioinformatics Approach
Significant Neurotoxicity
Critical Pe Riod (CP)
Ocular Dominance Index (ODI)
Online Access:https://doi.org/10.1038/s41598-018-34592-4

Internet

https://doi.org/10.1038/s41598-018-34592-4

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