Interferon-α-Enhanced CD100/Plexin-B1/B2 Interactions Promote Natural Killer Cell Functions in Patients with Chronic Hepatitis C Virus Infection

Interferon-α-Enhanced CD100/Plexin-B1/B2 Interactions Promote Natural Killer Cell Functions in Patients with Chronic Hepatitis C Virus Infection

BackgroundCD100, also known as Sema4D, is an immune semaphorin constitutively expressed on natural killer (NK) cells and T cells. As an immune activation molecule, CD100 has important immunoregulatory effects on NK functions by enhancing the interactions between NK cells and target cells. The aim of...

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Bibliographic Details
Main Authors: Yu He, Yonghong Guo, Chao Fan, Yingfeng Lei, Yun Zhou, Mingjie Zhang, Chuantao Ye, Guangxi Ji, Li Ma, Jianqi Lian, Jonathan P. Moorman, Zhi Q. Yao, Jiuping Wang, Chunqiu Hao, Ying Zhang, Zhansheng Jia
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Immunology
Subjects:
hepatitis C virus
natural killer cells
interferon-α
CD100
plexin-B1/B2
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01435/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01435/full

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