Insights Into the Effects of Mucosal Epithelial and Innate Immune Dysfunction in Older People on Host Interactions With Streptococcus pneumoniae

Insights Into the Effects of Mucosal Epithelial and Innate Immune Dysfunction in Older People on Host Interactions With Streptococcus pneumoniae

In humans, nasopharyngeal carriage of Streptococcus pneumoniae is common and although primarily asymptomatic, is a pre-requisite for pneumonia and invasive pneumococcal disease (IPD). Together, these kill over 500,000 people over the age of 70 years worldwide every year. Pneumococcal conjugate vacci...

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Bibliographic Details
Main Authors: Caroline M. Weight, Simon P. Jochems, Hugh Adler, Daniela M. Ferreira, Jeremy S. Brown, Robert S. Heyderman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
epithelium
pneumococcus (Streptococcus pneumoniae)
innate immunity
inflammageing
older individuals
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.651474/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.651474/full

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