Cancer Stem Cells, Bone and Tumor Microenvironment: Key Players in Bone Metastases

Tumor mass is constituted by a heterogeneous group of cells, among which a key role is played by the cancer stem cells (CSCs), possessing high regenerative properties. CSCs directly metastasize to bone, since bone microenvironment represents a fertile environment that protects CSCs against the immun...

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Bibliographic Details
Main Authors: Ilaria Roato, Riccardo Ferracini
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/2/56