Predictive modeling of in vivo response to gemcitabine in pancreatic cancer.

A clear contradiction exists between cytotoxic in-vitro studies demonstrating effectiveness of Gemcitabine to curtail pancreatic cancer and in-vivo studies failing to show Gemcitabine as an effective treatment. The outcome of chemotherapy in metastatic stages, where surgery is no longer viable, show...

Full description

Bibliographic Details
Main Authors: James J Lee, Justin Huang, Christopher G England, Lacey R McNally, Hermann B Frieboes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3777914?pdf=render