Building the Next Generation of Humanized Hemato-Lymphoid System Mice

Building the Next Generation of Humanized Hemato-Lymphoid System Mice

Since the late 1980s, mice have been repopulated with human hematopoietic cells to study the fundamental biology of human hematopoiesis and immunity, as well as a broad range of human diseases in vivo. Multiple mouse recipient strains have been developed and protocols optimized to efficiently genera...

Full description

Bibliographic Details
Main Authors: Tijana Martinov, Kelly M. McKenna, Wei Hong Tan, Emily J. Collins, Allie R. Kehret, Jonathan D. Linton, Tayla M. Olsen, Nour Shobaki, Anthony Rongvaux
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
humanized mice
immunity
hematopoiesis
infectious diseases
cancer
immunotherapies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.643852/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.643852/full

Similar Items