Quercetin Declines Apoptosis, Ameliorates Mitochondrial Function and Improves Retinal Ganglion Cell Survival and Function in In Vivo Model of Glaucoma in Rat and Retinal Ganglion Cell Culture In Vitro

Quercetin Declines Apoptosis, Ameliorates Mitochondrial Function and Improves Retinal Ganglion Cell Survival and Function in In Vivo Model of Glaucoma in Rat and Retinal Ganglion Cell Culture In Vitro

Glaucoma is a progressive neuropathy characterized by the loss of retinal ganglion cells (RGCs). Strategies that delay or halt RGC loss have been recognized as potentially beneficial for rescuing vision in glaucoma patients. Quercetin (Qcn) is a natural and important dietary flavonoid compound, wide...

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Bibliographic Details
Main Authors: Feng-Juan Gao, Sheng-Hai Zhang, Ping Xu, Bo-Qi Yang, Rong Zhang, Yun Cheng, Xu-Jiao Zhou, Wan-Jing Huang, Min Wang, Jun-Yi Chen, Xing-Huai Sun, Ji-Hong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
quercetin
retinal ganglion cells
glaucoma
apoptosis
mitochondria
neuroprotection
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00285/full

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http://journal.frontiersin.org/article/10.3389/fnmol.2017.00285/full

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