The evolving proteome of SARS-CoV-2 predominantly uses mutation combination strategy for survival

The evolving proteome of SARS-CoV-2 predominantly uses mutation combination strategy for survival

The knowledge about SARS-CoV-2 proteome variations is important to understand its evolutionary tactics and in drug/vaccine design. An extensive analysis of 125,747 whole proteome reveals 7915 recurring mutations (involving 5146 positions) during December2019-November 2020. Among these, 10 and 51 are...

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Bibliographic Details
Main Authors: L. Ponoop Prasad Patro, Chakkarai Sathyaseelan, Patil Pranita Uttamrao, Thenmalarchelvi Rathinavelan
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
SARS-CoV-2 mutations
Mutation combination
Viral evolution
Proteome variations
Evolutionary dynamics
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021002439

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http://www.sciencedirect.com/science/article/pii/S2001037021002439

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