Complexity and algorithms for copy-number evolution problems

Complexity and algorithms for copy-number evolution problems

Abstract Background Cancer is an evolutionary process characterized by the accumulation of somatic mutations in a population of cells that form a tumor. One frequent type of mutations is copy number aberrations, which alter the number of copies of genomic regions. The number of copies of each positi...

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Bibliographic Details
Main Authors: Mohammed El-Kebir, Benjamin J. Raphael, Ron Shamir, Roded Sharan, Simone Zaccaria, Meirav Zehavi, Ron Zeira
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Algorithms for Molecular Biology
Subjects:
Cancer
Maximum parsimony
Phylogeny
Somatic mutation
Copy-number variant
Online Access:http://link.springer.com/article/10.1186/s13015-017-0103-2

Internet

http://link.springer.com/article/10.1186/s13015-017-0103-2

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