Changes in gene expression associated with FTO overexpression in mice.

Changes in gene expression associated with FTO overexpression in mice.

Single nucleotide polymorphisms in the first intron of the fat-mass-and-obesity-related gene FTO are associated with increased body weight and adiposity. Increased expression of FTO is likely underlying this obesity phenotype, as mice with two additional copies of Fto (FTO-4 mice) exhibit increased...

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Bibliographic Details
Main Authors: Myrte Merkestein, James S McTaggart, Sheena Lee, Holger B Kramer, Fiona McMurray, Mathilde Lafond, Lily Boutens, Roger Cox, Frances M Ashcroft
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026227?pdf=render

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http://europepmc.org/articles/PMC4026227?pdf=render

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