Variable Immunogenic Potential of Wheat: Prospective for Selection of Innocuous Varieties for Celiac Disease Patients via in vitro Approach

Variable Immunogenic Potential of Wheat: Prospective for Selection of Innocuous Varieties for Celiac Disease Patients via in vitro Approach

Celiac Disease (CD) is a multifactorial, autoimmune enteropathy activated by cereal proteins in genetically predisposed individuals carrying HLA DQ2/8 genes. A heterogenous gene combination of the cereal prolamins is documented in different wheat genotypes, which is suggestive of their variable immu...

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Bibliographic Details
Main Authors: Jasmine Grover, Parveen Chhuneja, Vandana Midha, Jean Eric Ghia, Dipak Deka, Chandra Shekhar Mukhopadhyay, Neena Sood, Ramit Mahajan, Arshdeep Singh, Ramneek Verma, Ekta Bansal, Ajit Sood
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
celiac disease
immunogenicity
gluten
T-cell epitopes
in vitro analysis
cell proliferation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00084/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00084/full

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