Personalized Treatment Response Assessment for Rare Childhood Tumors Using Microcalorimetry–Exemplified by Use of Carbonic Anhydrase IX and Aquaporin 1 Inhibitors

Personalized Treatment Response Assessment for Rare Childhood Tumors Using Microcalorimetry–Exemplified by Use of Carbonic Anhydrase IX and Aquaporin 1 Inhibitors

We present a novel approach to a personalized therapeutic concept for solid tumors. We illustrate this on a rare childhood tumor for which only a generalized treatment concept exists using carbonic anhydrase IX and aquaporin 1 inhibitors. The use of microcalorimetry as a refined in vitro method for...

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Bibliographic Details
Main Authors: Stephanie J. Gros, Stefan G. Holland-Cunz, Claudiu T. Supuran, Olivier Braissant
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
caix inhibitor
aqp1
rare pediatric cancer
isothermal calorimetry
drug susceptibility
clear cell renal carcinoma
organotypic slice culture
Online Access:https://www.mdpi.com/1422-0067/20/20/4984

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https://www.mdpi.com/1422-0067/20/20/4984

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