Structural Identification of O-Linked Oligosaccharides Using Exoglycosidases and MSn Together with UniCarb-DB Fragment Spectra Comparison

Structural Identification of O-Linked Oligosaccharides Using Exoglycosidases and MSn Together with UniCarb-DB Fragment Spectra Comparison

The availability of specific exoglycosidases alongside a spectral library of O-linked oligosaccharide collision induced dissociation (CID) MS fragments, UniCarb-DB, provides a pathway to make the elucidation of O-linked oligosaccharides more efficient. Here, we advise an approach of exoglycosidase-d...

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Bibliographic Details
Main Authors: Liaqat Ali, Diarmuid T. Kenny, Catherine A. Hayes, Niclas G. Karlsson
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Metabolites
Subjects:
mass spectrometry
exoglycosidases
mucin
glycomics
Online Access:http://www.mdpi.com/2218-1989/2/4/648

Internet

http://www.mdpi.com/2218-1989/2/4/648

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