Interferon-γ Is a Crucial Activator of Early Host Immune Defense against Mycobacterium ulcerans Infection in Mice.

Buruli ulcer (BU), caused by infection with Mycobacterium ulcerans, is a chronic necrotizing human skin disease associated with the production of the cytotoxic macrolide exotoxin mycolactone. Despite extensive research, the type of immune responses elicited against this pathogen and the effector fun...

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Bibliographic Details
Main Authors: Raphael Bieri, Miriam Bolz, Marie-Thérèse Ruf, Gerd Pluschke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4749296?pdf=render