Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.

We assessed the virulence and anti-trypanosomal drug sensitivity patterns of Trypanosoma brucei rhodesiense (Tbr) isolates in the Kenya Agricultural and Livestock Research Organization-Biotechnology Research Institute (KALRO-BioRI) cryobank. Specifically, the study focused on Tbr clones originally i...

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Main Authors: Kariuki Ndung'u, Grace Adira Murilla, John Kibuthu Thuita, Geoffrey Njuguna Ngae, Joanna Eseri Auma, Purity Kaari Gitonga, Daniel Kahiga Thungu, Richard Kiptum Kurgat, Judith Kusimba Chemuliti, Raymond Ellie Mdachi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0229060