Autophagy facilitates antibody-enhanced dengue virus infection in human pre-basophil/mast cells.

Autophagy facilitates antibody-enhanced dengue virus infection in human pre-basophil/mast cells.

Dengue virus (DENV) infection can cause severe hemorrhagic disease in humans. Although the pathogenic mechanisms underlying severe DENV disease remain unclear, one of the possible contributing factors is antibody-dependent enhancement (ADE) which occurs when sub-neutralizing antibodies derived from...

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Bibliographic Details
Main Authors: Yi-Ting Fang, Shu-Wen Wan, Yi-Tien Lu, Ju-Han Yao, Chiou-Feng Lin, Li-Jin Hsu, Michael G Brown, Jean S Marshall, Robert Anderson, Yee-Shin Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4199741?pdf=render

Internet

http://europepmc.org/articles/PMC4199741?pdf=render

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