Expression of a Cu,Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of neuroblastoma cells to infectious injury

<p>Abstract</p> <p>Background</p> <p>Infections can aggravate the course of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS). Mutations in the anti-oxidant enzyme Cu,Zn superoxide dismutase (EC 1.15.1.1, SOD1) are associated with familial ALS. St...

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Bibliographic Details
Main Authors: Carrì Maria, Mitchell Timothy, Ebert Sandra, Balakrishnan Saju, Jaiswal Manoj, Zech Wolf-Dieter, Goos Miriam, Keller Bernhard U, Nau Roland
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/7/131