Preclinical models as patients’ avatars for precision medicine in colorectal cancer: past and future challenges

Abstract Colorectal cancer (CRC) is a complex and heterogeneous disease, characterized by dismal prognosis and low survival rate in the advanced (metastatic) stage. During the last decade, the establishment of novel preclinical models, leading to the generation of translational discovery and validat...

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Bibliographic Details
Main Authors: Erika Durinikova, Kristi Buzo, Sabrina Arena
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-021-01981-z