Gamma-irradiated rotavirus: A possible whole virus inactivated vaccine.

Rotavirus (RV) causes significant morbidity and mortality in developing countries, where children and infants are highly susceptible to severe disease symptoms. While live attenuated vaccines are available, reduced vaccine efficacy in developing countries illustrates the need for highly immunogenic...

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Bibliographic Details
Main Authors: Shabihah Shahrudin, Cheng Chen, Shannon C David, Eve V Singleton, Justin Davies, Carl D Kirkwood, Timothy R Hirst, Michael Beard, Mohammed Alsharifi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5991763?pdf=render