6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Suppresses Neuronal Apoptosis by Increasing Glycolysis and “cyclin-dependent kinase 1-Mediated Phosphorylation of p27 After Traumatic Spinal Cord Injury in Rats

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Suppresses Neuronal Apoptosis by Increasing Glycolysis and “cyclin-dependent kinase 1-Mediated Phosphorylation of p27 After Traumatic Spinal Cord Injury in Rats

Apoptosis is a vital pathological factor that accounts for the poor prognosis of traumatic spinal cord injury (t-SCI). The 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is a critical regulator for energy metabolism and proven to have antiapoptotic effects. This study aimed to investi...

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Bibliographic Details
Main Authors: Liansheng Gao, Chun Wang, Bing Qin, Tao Li, Weilin Xu, Cameron Lenahan, Guangyu Ying, Jianru Li, Tengfei Zhao, Yongjian Zhu, Gao Chen
Format: Article
Language:English
Published: SAGE Publishing 2020-08-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689720950226

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https://doi.org/10.1177/0963689720950226

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