Determining the Optimal Administration Conditions under Which MIF Exerts Neuroprotective Effects by Inducing BDNF Expression and Inhibiting Apoptosis in an in Vitro Stroke Model

Determining the Optimal Administration Conditions under Which MIF Exerts Neuroprotective Effects by Inducing BDNF Expression and Inhibiting Apoptosis in an in Vitro Stroke Model

Macrophage migration inhibitory factor (MIF) exerts neuroprotective effects against cerebral ischemia/reperfusion injury by inhibiting neuronal apoptosis and inducing the expression of brain-derived neurotrophic factor (BDNF). However, the optimal administration conditions of MIF are currently unkno...

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Bibliographic Details
Main Authors: Chul Jung, Mi Hee Kim, Ye Yeong Kim, Ji Ae Kim, Eun Jae Ko, Seung Hak Lee, Dae Yul Kim
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Brain Sciences
Subjects:
macrophage migration inhibitory factor
neuroprotection
brain-derived neurotrophic factor
apoptosis
ischemic stroke
Online Access:https://www.mdpi.com/2076-3425/11/2/280

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https://www.mdpi.com/2076-3425/11/2/280

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