Variable Expression of Notch1 and Pax5 in Classical Hodgkin Lymphoma and Infection with Epstein–Barr in Pediatric Patients

Variable Expression of Notch1 and Pax5 in Classical Hodgkin Lymphoma and Infection with Epstein–Barr in Pediatric Patients

NOTCH1 and PAX5 participate in the proliferation and differentiation of B and T lymphocytes. Their expression can be modified by activation of NOTCH1, induced by the Epstein–Barr (EBV) viral proteins identified as LMP1 and LMP2. To identify whether PAX5, NOTCH1, and EBV latency genes participate in...

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Bibliographic Details
Main Authors: Icela Palma-Lara, Ana Elena Sánchez-Aldana, Elva Jiménez-Hernández, Octavio Martínez-Villegas, Juan Carlos Núñez-Enríquez, Juan Manuel Mejía-Aranguré, Sara A. Ochoa, Juan Xicohtencatl-Cortes, Ariadnna Cruz-Córdova, Sergio Zavala-Vega, Mariana García-Jiménez, Alejandra Contreras-Ramos, José Refugio Torres-Nava, Guillermo Mora-Ramiro, José Arellano-Galindo
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Microorganisms
Subjects:
Epstein–Barr virus 1
Hodgkin lymphoma
NOTCH1
PAX5
Online Access:https://www.mdpi.com/2076-2607/8/6/958

Internet

https://www.mdpi.com/2076-2607/8/6/958

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