p53 Protein Detected By Immunohistochemical Staining is Not Always Mutant
The expression of the tumour suppressor gene p53 was analyzed in a variety of human solid tumours by immunohistochemistry and direct DNA sequencing. Positive nuclear staining using a panel of anti-p53 antibodies was used to select tumours for further genetic analysis. Using PCR amplification followe...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
1993-01-01
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| Series: | Disease Markers |
| Online Access: | http://dx.doi.org/10.1155/1993/480686 |