The Role of the Central Nervous System Microenvironment in Pediatric Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is the most common cancer in children. While survival rates for ALL have improved, central nervous system (CNS) relapse remains a significant cause of treatment failure and treatment-related morbidity. Accordingly, there is a need to identify more efficacious and l...

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Bibliographic Details
Main Authors: Peter M. Gordon, Nathan P. Gossai
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fped.2017.00090/full