Interactions of Biocidal Polyhexamethylene Guanidine Hydrochloride and Its Analogs with POPC Model Membranes

Interactions of Biocidal Polyhexamethylene Guanidine Hydrochloride and Its Analogs with POPC Model Membranes

The bacterial membrane-targeted polyhexamethylene guanidine hydrochloride (PHGH) and its novel analog polyoctamethylene guanidine hydrochloride (POGH) had excellent antimicrobial activities against antibiotics-resistant bacteria. However, the biocompatibility aspects of PHGH and POGH on the phosphol...

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Bibliographic Details
Main Authors: Xuliang Luo, Ziran Jiang, Niya Zhang, Zixin Yang, Zhongxin Zhou
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Polymers
Subjects:
polyhexamethylene guanidine hydrochloride
membrane
POPC
hemolytic activity
dye leakage
Online Access:https://www.mdpi.com/2073-4360/9/10/517

Internet

https://www.mdpi.com/2073-4360/9/10/517

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