Development and validation of a prognostic model to predict death in patients with traumatic bleeding, and evaluation of the effect of tranexamic acid on mortality according to baseline risk: a secondary analysis of a randomised controlled trial

Bibliographic Details
Main Authors:	P Perel, D Prieto-Merino, H Shakur, I Roberts
Format:	Article
Language:	English
Published:	NIHR Journals Library 2013-06-01
Series:	Health Technology Assessment
Online Access:	https://doi.org/10.3310/hta17240

CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury, a nested randomised, placebo-controlled trial.
by: P Perel, et al.
Published: (2012-03-01)

The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients
by: I Roberts, et al.
Published: (2013-03-01)

Tranexamic Acid – a Recipe for Saving Lives in Traumatic Bleeding
by: Ian Roberts
Published: (2011-12-01)

Tranexamic Acid: A Recipe for Saving Lives in Traumatic Bleeding
by: I Roberts
Published: (2011-09-01)

Tranexamic acid: A recipe for saving lives in traumatic bleeding
by: Ian Roberts
Published: (2012-01-01)

Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial
by: Ker Katharine, et al.
Published: (2012-03-01)

Giving tranexamic acid to reduce surgical bleeding in sub-Saharan Africa: an economic evaluation
by: Perel Pablo, et al.
Published: (2010-02-01)

Intracranial bleeding in patients with traumatic brain injury: A prognostic study
by: Mooney Jane, et al.
Published: (2009-08-01)

Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial.
by: Carla Guerriero, et al.
Published: (2011-05-01)

A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan [version 3; peer review: 2 approved, 2 approved with reservations]
by: Abda Mahmood, et al.
Published: (2019-11-01)

A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan [version 2; peer review: 2 approved, 1 approved with reservations]
by: Abda Mahmood, et al.
Published: (2019-01-01)

A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])
by: Abda Mahmood, et al.
Published: (2017-07-01)

Cost-effectiveness analysis of tranexamic acid for the treatment of traumatic brain injury, based on the results of the CRASH-3 randomised trial: a decision modelling approach
by: Ian Roberts, et al.
Published: (2020-09-01)

Tranexamic acid in non-traumatic intracranial bleeding: a systematic review and meta-analysis
by: Jean-Baptiste Bouillon-Minois, et al.
Published: (2021-07-01)

CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial
by: Dewan Yashbir, et al.
Published: (2012-06-01)

Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial
by: Katharine Ker, et al.
Published: (2018-12-01)

Topical tranexamic acid as a novel treatment for bleeding peptic ulcer: A randomised controlled trial
by: Mandana Rafeey, et al.
Published: (2016-01-01)

The significance of tranexamic acid in bleeding ulcers
by: Ruborg, Rebecca
Published: (2014)

Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial
by: Amy Brenner, et al.
Published: (2019-07-01)

Risk factors for vascular occlusive events and death due to bleeding in trauma patients; an analysis of the CRASH-2 cohort.
by: Louise Pealing, et al.
Published: (2012-01-01)

Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT
by: Ian Roberts, et al.
Published: (2021-04-01)

The effect of Tranexamic acid on cardiac surgery bleeding
by: Mohammad Esmaeelzadeh, et al.
Published: (2014-02-01)

In adult patients presenting as emergencies with upper gastrointestinal bleeding, does tranexamic acid decrease mortality?
by: Tim Nutbeam
Published: (2015-06-01)

Validation of the BATT score for prehospital risk stratification of traumatic haemorrhagic death: usefulness for tranexamic acid treatment criteria
by: Francois-Xavier Ageron, et al.
Published: (2021-01-01)

Systematic review of prognostic models in traumatic brain injury
by: Roberts Ian, et al.
Published: (2006-11-01)

Tranexamic acid for the prevention and treatment of bleeding in surgery, trauma and bleeding disorders: a narrative review
by: Anna Ockerman, et al.
Published: (2021-08-01)

Bronchoscopic instillation of tranexamic acid to control bronchopulmonary bleeding
by: Emad El-Din A. Korraa, et al.
Published: (2017-07-01)

Is tranexamic acid effective for acute upper gastrointestinal bleeding?
by: Sebastián Flores, et al.
Published: (2015-12-01)

Preventive and therapeutic effects of tranexamic acid on postpartum bleeding
by: Samaneh Solltani, et al.
Published: (2014-12-01)

Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial
by: Amy Brenner, et al.
Published: (2020-11-01)

Tranexamic acid for bleeding in a child with extensive small bowel angiodysplasia
by: Ryo Tamura, et al.
Published: (2020-08-01)

The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial
by: Allen Elizabeth, et al.
Published: (2010-04-01)

Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial [version 1; referees: 2 approved]
by: Ian Roberts, et al.
Published: (2018-07-01)

Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury
by: Shakur Haleema, et al.
Published: (2008-11-01)

A randomised, open-label, comparative study of tranexamic acid microinjections and tranexamic acid with microneedling in patients with melasma
by: Leelavathy Budamakuntla, et al.
Published: (2013-01-01)

The effect of tranexamic acid in reduction of bleeding in coronary artery bypass grafting
by: K.Kazem-Nejad (MD), et al.
Published: (2006-04-01)

Comparison Of Effects Of Autotransfusion And Tranexamic Acid On Post Cardiopulmonary Bypass Bleeding
by: Mehr AeinA, et al.
Published: (2003-11-01)

Efficacy of Tranexamic Acid in reducing intra-operative bleeding during tonsillectomy
by: Asmatullah Achakzai, et al.
Published: (2020-11-01)

Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial [version 2; referees: 3 approved, 1 approved with reservations]
by: Ian Roberts, et al.
Published: (2018-09-01)

Development and validation of a prognostic model to predict death in patients with traumatic bleeding, and evaluation of the effect of tranexamic acid on mortality according to baseline risk: a secondary analysis of a randomised controlled trial

Similar Items

Similar Items