Characterization of Polysaccharide A Response Reveals Interferon Responsive Gene Signature and Immunomodulatory Marker Expression

Characterization of Polysaccharide A Response Reveals Interferon Responsive Gene Signature and Immunomodulatory Marker Expression

Polysaccharide A (PSA), a capsular carbohydrate from the commensal gut bacteria Bacteroides fragilis, has been shown to possess both potent T cell-dependent pro- and anti-inflammatory properties. PSA is able to induce abscess and adhesion formation in sepsis models, but can also inhibit asthma, infl...

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Bibliographic Details
Main Authors: Carlos A. Alvarez, Mark B. Jones, John Hambor, Brian A. Cobb
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
polysaccharides
T cells
interferon
co-regulatory receptors
microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.556813/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.556813/full

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