Inactivation of Protein Tyrosine Phosphatases by Peracids Correlates with the Hydrocarbon Chain Length

Inactivation of Protein Tyrosine Phosphatases by Peracids Correlates with the Hydrocarbon Chain Length

Background/Aims: Protein tyrosine phosphatases are crucial enzymes controlling numerous physiological and pathophysiological events and can be regulated by oxidation of the catalytic domain cysteine residue. Peracids are highly oxidizing compounds, and thus may induce inactivation of PTPs. The aim o...

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Bibliographic Details
Main Authors: Alicja Kuban-Jankowska, Magdalena Gorska, Jack A. Tuszynski, Cassandra D. M. Churchill, Philip Winter, Mariusz Klobukowski, Michal Wozniak
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Peracids (peroxyacids, percarboxylic acids)
Catalytic cysteine residue
Protein tyrosine phosphatases (PTPs)
Online Access:http://www.karger.com/Article/FullText/430280

Internet

http://www.karger.com/Article/FullText/430280

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