Epigenetic Inactivation of the Tumor Suppressor <i>IRX1</i> Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis
<i>Iroquois homeobox</i> (IRX) encodes members of homeodomain containing genes which are involved in development and differentiation. Since it has been reported that the <i>IRX1</i> gene is localized in a lung cancer susceptibility locus, the epigenetic regulation and functio...
Main Authors: | Miriam M. Küster, Marc A. Schneider, Antje M. Richter, Sarah Richtmann, Hauke Winter, Mark Kriegsmann, Soni S. Pullamsetti, Thorsten Stiewe, Rajkumar Savai, Thomas Muley, Reinhard H. Dammann |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/12/3528 |
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