Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling

Piwi reduction in the aged niche eliminates germline stem cells via Toll-GSK3 signaling

Retrotransposons are known to be involved in aging. Here the authors show that the retrotransposon silencer Piwi contributes to germline stem cell loss during aging in Drosophila.

Bibliographic Details
Main Authors: Kun-Yang Lin, Wen-Der Wang, Chi-Hung Lin, Elham Rastegari, Yu-Han Su, Yu-Tzu Chang, Yung-Feng Liao, Yi-Chieh Chang, Haiwei Pi, Bo-Yi Yu, Shu-Hwa Chen, Chung-Yen Lin, Mei-Yeh Lu, Tsu-Yi Su, Fei-Yang Tzou, Chih-Chiang Chan, Hwei-Jan Hsu
Format: Article
Language:English
Published: Nature Publishing Group 2020-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16858-6

Internet

https://doi.org/10.1038/s41467-020-16858-6

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