MiRNA therapeutics based on logic circuits of biological pathways

MiRNA therapeutics based on logic circuits of biological pathways

Abstract Background In silico experiments, with the aid of computer simulation, speed up the process of in vitro or in vivo experiments. Cancer therapy design is often based on signalling pathway. MicroRNAs (miRNA) are small non-coding RNA molecules. In several kinds of diseases, including cancer, h...

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Bibliographic Details
Main Authors: Valeria Boscaino, Antonino Fiannaca, Laura La Paglia, Massimo La Rosa, Riccardo Rizzo, Alfonso Urso
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Bioinformatics
Subjects:
miRNA therapeutics
Drug discovery
Cancer pathway
Logic circuit
Boolean network
Online Access:http://link.springer.com/article/10.1186/s12859-019-2881-7

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http://link.springer.com/article/10.1186/s12859-019-2881-7

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