Mesenchymal stem cells increase proliferation but do not change quiescent state of osteosarcoma cells: Potential implications according to the tumor resection status

Mesenchymal stem cells increase proliferation but do not change quiescent state of osteosarcoma cells: Potential implications according to the tumor resection status

Conventional therapy of primary bone tumors includes surgical excision with wide resection, which leads to physical and aesthetic defects. For reconstruction of bone and joints, allografts can be supplemented with mesenchymal stem cells (MSCs). Similarly, adipose tissue transfer (ATT) is supplemente...

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Bibliographic Details
Main Authors: Pierre Avril, Louis-Romée Le Nail, Meadhbh Á. Brennan, Philippe Rosset, Gonzague De Pinieux, Pierre Layrolle, Dominique Heymann, Pierre Perrot, Valérie Trichet
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Journal of Bone Oncology
Subjects:
Mesenchymal stem cell
Osteosarcoma
Adipose tissue transfer
Cell cycle
Quiescence
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137415300373

Internet

http://www.sciencedirect.com/science/article/pii/S2212137415300373

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